1 any substance that causes injury or illness or death of a living organism [syn: poisonous substance]
2 anything that harms or destroys; "the poison of fascism"
1 spoil as if by poison; "poison someone's mind"; "poison the atmosphere in the office"
2 kill by its poison; "This mushrooms can kill"
3 kill with poison; "She poisoned her husband"
4 add poison to; "Her husband poisoned her drink in order to kill her" [syn: envenom]
5 administer poison to; "She poisoned her husband but he did not die"
- , /ˈpɔɪz(ə)n/, /"pOIz(@)n/
- Rhymes with: -ɔɪzən
EtymologyFrom puison < potio. See also potion and potable.
- poison gas
- poison hemlock
- poison ivy
- poison oak
- poison pen
- poison pill
- poison sumac
- rat poison
- what's your poison
substance harmful to a living organism
- Albanian: helm
- Arabic: سم
- Bosnian: otrov
- Bulgarian: отрова
- CJKV Characters: 毒
- Catalan: verí, metzina
- Chinese: 毒物, 毒药
- Croatian: otrov
- Czech: jed
- Danish: gift
- Dutch: gif, vergif, vergift
- Esperanto: veneno
- Estonian: mürk
- Faroese: gift, eitur
- Finnish: myrkky
- French: poison
- German: Gift, Giftstoff
- Greek: δηλητήριο, φαρμάκι, ιός, φόλα
- Hebrew: רעל, סם
- Hindi: विष, ज़हर, जहर
- Hungarian: méreg
- Indonesian: racun, bisa (of snake)
- Interlingua: veneno, toxico
- Italian: veleno
- Japanese: 毒
- Korean: 독
- Kurdish: jehr, jar, دهرمانخوارد, ژههر
- Latin: venenum, toxicum
- Lithuanian: nuodai
- Norwegian: gift
- Old English: ator
- Persian: زهر
- Polish: trucizna, jad
- Portuguese: veneno, peçonha, tóxico
- Russian: яд
- Scottish Gaelic: átor, nimh
- Cyrillic: отров
- Roman: otrov
- Cyrillic: отров
- Slovak: jed
- Slovene: strup
- Spanish: veneno
- Swahili: sumu
- Swedish: gift
- Telugu: విషం
- Turkish: zehir
- Urdu: زہر
something that harms
- To use poison to kill
or paralyse somebody
- The assassin poisoned the king.
- To pollute; to cause
some part of the environment to become
- That factory is poisoning the river.
- To cause something to become much worse
- Suspicion will poison their relationship.
- He poisoned the mood in the room with his non-stop criticism.
- Suspicion will poison their relationship.
- To cause someone to hate or to have unfair negative opinions
- She's poisoned him against all his old friends.
to use poison to kill or paralyse
- Bulgarian: тровя, отравям
- Catalan: emmetzinar, enverinar
- Czech: otrávit
- Danish: forgifte
- Dutch: vergiftigen
- Faroese: eitra
- French: empoisoner
- Estonian: mürgitama
- Finnish: myrkyttää
- French: empoisonner
- German: vergiften
- Hungarian: megmérgez
- Indonesian: racun
- Interlingua: invenenar, intoxicar
- Italian: avvelenare, intossicare
- Japanese: 毒を混入する (mix with poison), 毒を盛る
- Kurdish: jehr kirin, jehr dan
- Latin: veneno
- Polish: truć, zatruwać, otruć
- Portuguese: envenenar, empeçonhar, intoxicar
- Slovak: otráviť
- Swedish: förgifta
- Online Etymology Dictionary}}
In the context of biology, poisons are substances that can cause damage, illness, or death to organisms, usually by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by an organism. Legally and in hazardous chemical labelling, poisons are especially toxic substances; less toxic substances are labelled "harmful", "irritant", or not labelled at all.
In medicine (particularly veterinary) and in zoology, a poison is often distinguished from a toxin and a venom. Toxins are poisons produced via some biological function in nature, and venoms are usually defined as biologic toxins that are injected by a bite or sting to cause their effect, while other poisons are generally defined as substances which are absorbed through epithelial linings such as the skin or gut.
Some poisons are also toxins, usually referring to naturally produced substances, such as the bacterial proteins that cause tetanus and botulism. A distinction between the two terms is not always observed, even among scientists.
Animal toxins that are delivered subcutaneously (e.g. by sting or bite) are also called venom. In normal usage, a poisonous organism is one that is harmful to consume, but a venomous organism uses poison to defend itself while still alive. A single organism can be both venomous and poisonous.
The derivative forms "toxic" and "poisonous" are synonymous.
Within chemistry and physics, a poison is a substance that obstructs or inhibits a reaction, for example by binding to a catalyst. For example, see nuclear poison.
Paracelsus, the father of toxicology, once wrote: "Everything is poison, there is poison in everything. Only the dose makes a thing not a poison." The phrase "poison" is often used colloquially to describe any harmful substance, particularly corrosive substances, carcinogens, mutagens, teratogens and harmful pollutants, and to exaggerate the dangers of chemicals. The legal definition of "poison" is stricter. A medical condition of poisoning can also be caused by substances that are not legally required to carry the label "poison".
Uses of poison
Poisons are usually not used for their toxicity, but may be used for their other properties. The property of toxicity itself has limited applications: mainly for controlling pests and weeds, and for preserving building materials and food stuffs. Where possible, specific agents which are less poisonous to humans have come to be preferred, but exceptions such as phosphine continue in use.
Throughout human history, intentional application of poison has been used as a method of assassination, murder, suicide and execution. As a method of execution, poison has been ingested, as the ancient Athenians did (see Socrates), inhaled, as with carbon monoxide or hydrogen cyanide (see gas chamber), or injected (see lethal injection). Many languages describe lethal injection with their corresponding words for "poison shot". Poison was also employed in gunpowder warfare. For example, the 14th century Chinese text of the Huo Long Jing written by Jiao Yu outlined the use of a poisonous gunpowder mixture to fill cast iron grenade bombs.
Poisonous materials are often used for their chemical or physical properties other than being poisonous. The most effective, easiest, safest, or cheapest option for use in a chemical synthesis may be a poisonous material. Particularly in experimental laboratory syntheses a specific reactivity is used, despite the toxicity of the reagent. Chromic acid is an example of such a "simple to use" reagent. Many technical applications call for some specific physical properties; a toxic substance may possess these properties and therefore be superior. Reactivity, in particular, is important. Hydrogen fluoride (HF), for example, is poisonous and extremely corrosive. However, it has a high affinity (free energy) for silicon, which is exploited by using HF to etch glass or to manufacture silicon semiconductor chips.
Acute poisoning is exposure to a poison on one occasion or during a short period of time. Symptoms develop in close relation to the exposure. Absorption of a poison is necessary for systemic poisoning. In contrast, substances that destroy tissue but do not absorb, such as lye, are classified as corrosives rather than poisons.
Chronic poisoning is long-term repeated or continuous exposure to a poison where symptoms do not occur immediately or after each exposure. The patient gradually becomes ill, or becomes ill after a long latent period. Chronic poisoning most commonly occurs following exposure to poisons that bioaccumulate such as mercury and lead.
Contact or absorption of poisons can cause rapid death or impairment. Agents that act on the nervous system can paralyze in seconds or less, and include both biologically derived neurotoxins and so-called nerve gases, which may be synthesized for warfare or industry.
Inhaled or ingested cyanide as used as method of execution on US gas chambers almost instantly starves the body of energy by inhibiting the enzymes in mitochondria that make ATP. Intravenous injection of an unnaturally high concentration of potassium chloride, such as in the execution of prisoners in parts of the United States, quickly stops the heart by eliminating the cell potential necessary for muscle contraction.
Most (but not all) biocides, including pesticides, are created to act as poisons to target organisms, although acute or less observable chronic poisoning can also occur in non-target organism, including the humans who apply the biocides and other beneficial organisms. For example, the herbicide 2,4-D imitates the action of a plant hormone, to the effect that the lethal toxicity is specific to plants. Indeed, 2,4-D is not a poison, but classified as "harmful" (EU).
Many substances regarded as poisons are toxic only indirectly, by toxication. An example is "wood alcohol" or methanol, which is not poisonous itself, but is chemically converted to toxic formaldehyde and formic acid in the liver. Many drug molecules are made toxic in the liver, and the genetic variability of certain liver enzymes makes the toxicity of many compounds differ between individuals.
The study of the symptoms, mechanisms, treatment and diagnosis of biological poisoning is known as toxicology.
Exposure to radioactive substances can produce radiation poisoning, an unrelated phenomenon.
- Poison Control Centers (In the US reachable at 1-800-222-1222 at all hours) provide immediate, free, and expert treatment advice and assistance over the telephone in case of suspected exposure to poisons or toxic substances.
- If the toxin was recently ingested, absorption of the substance
may be able to be decreased through gastric decontamination. This
may be achieved using activated
bowel irrigation, or nasogastric
aspiration. Routine use of emetics (syrup of
Ipecac) and cathartics are no longer recommended.
- Activated charcoal is the treatment of choice to prevent absorption of the poison. It is usually administered when the patient is in the emergency room. However, charcoal is ineffective against metals, Na, K, alcohols, glycols, acids, and alkalis.
- Whole bowel irrigation cleanses the bowel, this is achieved by giving the patient large amounts of a polyethylene glycol solution. The osmotically balanced polyethylene glycol solution is not absorbed into the body, having the effect of flushing out the entire gastrointestinal tract. Its major uses are following ingestion of sustained release drugs, toxins that are not absorbed by activated charcoal (i.e. lithium, iron), and for the removal of ingested packets of drugs (body packing/smuggling).
- Gastric lavage, commonly known as a stomach pump, is the insertion of a tube into the stomach, followed by administration of water or saline down the tube. The liquid is then removed along with the contents of the stomach. Lavage has been used for many years as a common treatment for poisoned patients. However, a recent review of the procedure in poisonings suggests no benefit. It is still sometimes used if it can be performed within 1 h of ingestion and the exposure is potentially life threatening.
- Nasogastric aspiration involves the placement of a tube via the nose down into the stomach, the stomach contents are then removed via suction. This procedure is mainly used for liquid ingestions where activated charcoal is ineffective, i.e. ethylene glycol.
- Emesis (i.e. induced by ipecac) is no longer recommended in poisoning situations.
- Cathartics were postulated to decrease absorption by increasing the expulsion of the poison from the gastrointestinal tract. There are two types of cathartics used in poisoned patients; saline cathartics (sodium sulfate, magnesium citrate, magnesium sulfate) and saccharide cathartics (sorbitol). They do not appear to improve patient outcome and are no longer recommended.
AntidotesSome poisons have specific antidotes:
- In the majority of poisonings the mainstay of management is providing supportive care for the patient, i.e. treating the symptoms rather than the poison.
poison in Bulgarian: Отрова
poison in Catalan: Verí
poison in Czech: Jed
poison in Danish: Gift
poison in German: Gift
poison in Modern Greek (1453-): Δηλητήριο
poison in Esperanto: Veneno
poison in Spanish: Veneno
poison in Estonian: Mürk
poison in Basque: Pozoi
poison in Finnish: Myrkyllisyys
poison in French: Poison
poison in Galician: Veleno
poison in Hebrew: רעל
poison in Croatian: Otrov
poison in Hungarian: Méreg
poison in Indonesian: Racun
poison in Italian: Veleno
poison in Japanese: 毒
poison in Korean: 독
poison in Latin: Venenum
poison in Luxembourgish: Gëft
poison in Lithuanian: Nuodas
poison in Latvian: Inde
poison in Dutch: Vergif
poison in Norwegian Nynorsk: Gift
poison in Norwegian: Gift
poison in Polish: Trucizna
poison in Portuguese: Veneno
poison in Quechua: Miyu
poison in Romanian: Substanţe toxice
poison in Russian: Яд
poison in Serbo-Croatian: Otrov
poison in Simple English: Poison
poison in Slovak: Jed
poison in Slovenian: Strup
poison in Serbian: Отров
poison in Swedish: Gift
poison in Tajik: Заҳр
poison in Turkish: Zehir
poison in Ukrainian: Отрути
poison in Vietnamese: Chất độc
poison in Chinese: 毒物
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